Actress who won a 2005 Primetime Emmy Award for Outstanding Lead Actress for starring as Lynette Scavo on the television series Desperate Housewives.
She played a trans-woman in the film Transamerica, which won her a Golden Globe Award.
She starred in Desperate Housewives with Teri Hatcher.
She attended a private boarding high school before attending New York University.
She married William H. Macy in 1997 and the couple welcomed their daughter, Sophia, in 2000.