Well-known for playing the supporting role in the series Ang Tanging Ina, Eugene Domingo is a talented comedienne, actress, and presenter from Philippines. She has taken numerous leading as well as supporting roles in various types of films, including Bahay Kubo, Ang Babae Sa Septic Tank, Here Comes the Bride, Petrang Kabayo, Mamarazzi, Working Girls 2010, etc. With her great performance and contribution to entertainment industry, she received many awards as Best Supporting Actress, Best Actress, Best Leading Actress at Cinemalaya 2011, 10th Gawad Tanglaw for Films 2012, People's Choice Award 2012 as well as Best Game Show Host, Best Comedy Show Host, etc.
Born in Manila, Philippines, Domingo showed her interest in acting at her early age. When she was small, she usually imitated actions of teachers and people around her and she started pursuing acting dream after watching a musical held at the CCP Complex. She attended University of the Philippines to major in Theatre Arts and had a minor role in film Emma Salazar Case in 1991.
Little was known about her personal relationship.